Solid phase synthesis usually refers to the reaction between the activity of functional groups on Solid Phase support (such as resin) and dissolved reagent in organic solvents.


In the solid phase synthesis of peptide, the extension of peptide is proceeding on insoluble polystyrene resin support. C-terminal of polypeptide reaction with chloromethyleted polystyrene (chlorinated benzyl ester resin) first to form benzyl ester, and then extend peptide chain by the order of the primary structure of protected amino acid added individually.


Solid phase method is simple than liquid phase method, shorter time, and can be automated, and has been applied in the pharmaceutical industry in China.


Solid Phase Synthesis Frits are made by UHWM-PE, has a wide range of solvent compatibility.


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Frits for Solid Phase Synthesis Columns


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